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  1. Nature
    https://www.nature.com/articles/s41419-021-03743-3

    CircRNAs: role in human diseases and potential use as biomarkers

    • Breast cancer is the most common cancer in females and it can be classified in three major cancer subtypes according to estrogen or progesterone receptor expression and ERBB2 gene amplification: hormone r… 展开

    Abstract

    Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a … 展开

    Nature
    Facts

    •circRNAs are single-stranded circles of RNA, which form highly stable closed loops.
    •circRNAs can have different functions. Among these, th… 展开

    Nature
    Open questions

    •Are there yet unknown features controlling circRNA biogenesis?
    •Are there still undiscovered functional aspects and mechanisms of circRNAs?
    •How do circRN… 展开

    Nature
    Introduction

    Circular RNAs (circRNAs) are covalently closed circular RNA molecules recently reconsidered for their important roles in cancer and in other human diseases1,2,3. Since 2013, whe… 展开

    Nature
    Biogenesis and function of circRNAs

    CircRNAs can derive from exons, introns, antisense, 5′ or 3′ untranslated and intergenic genomic regions27. Exonic circRNAs (ecircRNAs) represent the most abundant specie… 展开

    Nature
    反馈
    目录
    Abstract
    Facts
    Open questions
    Introduction
    Biogenesis and function of circRNAs
    Do circular RNAs contribute to TGF--induced EMT and metastasis in NSCLC?
     
  1. circRNA论坛
    http://www.circrna.com.cn/?p=10771

    Nat Commun丨四川大学华西医院彭勇教授揭示环状RNA通过增 …

  2. CircRNA EMT的图片

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  3. Springer
    https://link.springer.com/article/10.1007/s00018-024-05236-w

    Circular RNAs in EMT-driven metastasis regulation ... - Springer

  4. Nature
    https://www.nature.com/articles/s41568-024-00721-7

    Circular RNA in cancer - Nature Reviews Cancer

  5. Nature
    https://www.nature.com/articles/s41467-023-42571-1

    A circular RNA activated by TGFβ promotes tumor metastasis …

  6. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11088560

    Circular RNAs in EMT-driven metastasis regulation: modulation of …

  7. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140110

    Exosome-Associated circRNAs as Key Regulators of EMT in Cancer

  8. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894079

    Insights Into the Role of CircRNAs: Biogenesis, Characterization ...

  9. PubMed
    https://pubmed.ncbi.nlm.nih.gov/29844124

    Twist1 Regulates Vimentin through Cul2 Circular RNA to Promote …

  10. PubMed
    https://pubmed.ncbi.nlm.nih.gov/30261900

    Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-β-induced ...